Our business started with developing technology and manufacturing high-quality quaternary ammonium / phosphonium hydroxides for global market place, focusing on zeolite, pharma and epoxy coatings industries.
With our vast experience in synthetic organic chemistry and international regulatory fields, we have recently diversified into contract research / custom synthesis.
Our capabilities include lab-scale to kilo lab-scale synthesis of specialty chemicals / fine chemicals including key drug intermediates (from milligram to kilogram scale) under a strict GLP / cGMP environment.
We follow the modern concepts of Quality by Deign (QbD) and Process Analytical technology (PAT) to achieve the desired quality of the end products in a consistent manner. We minimize the potential for deviations and errors by implementing some relevant quality systems.
Some key lab instruments / equipments are enclosed in Annexure-I. We follow third-party evaluation / approval system while outsourcing any analytical testing activity to ensure GLP.
We have lab-scale reaction capabilities for handling reactions such as hydrogenations, halogenations, organo-metallic reactions, cross-coupling reactions, Wittig reaction, hydrolysis, esterification, oxidation, reduction etc. Besides this, we also have production facility for producing Kg to tons of phase transfer catalysts and quaternary ammonium hydroxides (details are given below).
We also have expertise in ion-exchange resin technology (special applications such as drug recovery from process streams, purification of drugs, specialty chemicals such as glycol, sugar, gelatine, and glucose purification), reverse osmosis, ultra-filtration and electro-dialysis from lab to commercial scale.
With our educational background and experience in synthetic organic chemistry we are quite capable of taking up complex projects for our clients from the pharmaceutical sector which requires concentration, flexibility, innovation and sometimes also creativity. Our extensive experience as a synthetic organic chemist helps us finding optimum solutions for new tasks as well.

We assist clients until the agreed objectives are met, keeping smooth communications with them and responding to their instructions and requests.

We make our chemical and technical know-how available to you for custom synthesis tasks and innovative research. This will enable you to concentrate on your core business and even save you expenditure for additional infrastructure and personnel.

For any of your above requirement, please e-mail us. We shall be happy to meet your GLC / cGMP requirements for the Custom Synthesis or Fine Chemicals as per the standards.

Many base-promoted organic reactions use metal hydroxides such as NaOH/KOH. However the finished products’ specs may not match the desired metal levels as these metal impurities may get carried into them. Solubility of these salts in solvents other than water and low MW alcohols is quite poor.

Other strong bases such as LDA, K-t-BuO, BuLi can be synthesized in situ. But they also pose problems e.g. LDA requires additional co-solvents such 1,2-dimethoxyethane while K-t-BuO requires high MW metal alkoxides and may also contaminate the product by leaving the non-volatile matter that is difficult to remove.

So the quaternary ammonium hydroxides (QAHs) are quite a good choice for many base-promoted organic reactions. Most of the QAHs are soluble in almost all organic solvents. Many of them can be used in anhydrous conditions and even upon decomposition, they do not leave any residual matter in the product. In fact the decomposition of QAHs leaves the volatile matter that can be easily removed under diminished pressure.

Few reactions where QAHs can be used are:

Polysiloxane and polycarbonate synthesis
Ester hydrolysis
Isomerisation reactions
Epoxidation of α, β-unsaturated ketones
Ketonic polymers
Aldol and Claisen Condensations
Catalytic alkynylition of aldehydes and keatones

The specialty salts such as tetrabutylammonium fluoride (TBAF) can be used in the cyclization reaction owing to its having nucleophilic character.

Please refer Annexure-I for the list of our instruments/equipments and Annexure-II for our range of products which we manufacture and supply.